Microsoft Disk Clean-up (Cleanmgr) is Going Away in Windows 10. Try Cleanmgr+Arrow up
If DEP is turned on for all programs, it can cause issues with certain programs.
DEP will sometimes shut down a program or process without any notification if it violates DEP.
You can turn off Data Execution Prevention for a particular program in Windows by following the steps below.
1. Go to Start > Control Panel > System.
2. Go to the Advanced tab and access the Performance Settings.
3. Go to the Data Execution Prevention tab.
4. Now select the option "Turn on DEP for all programs and services except those I select"
In this case, set a exception for CloneApp.
A reboot will be required to implement the change.
Note that you can turn off DEP globally for the entire system, but it’s not recommended as it makes your computer less secure.
Another scenario what was said to me by the Users and what helped
.. is that Microsoft Enhanced Mitigation Experience Toolkit (EMET) was set to Maximum Security.
Reducing it to Recommended Settings allowed CloneApp to run.
CloneApp is a free and portable program for Microsoft Windows devices to back up preferences, settings and other data of supported applications. CloneApp is highly customizable and can a be extended via "plug-ins", plain text files which define exactly which files, folders and Registry keys the program should preserve.
It requires Windows 10, 8.1, 8, 7 or Vista, including both 32-bit and 64-bit versions.